Tetrahedron letters

Regioselective synthesis of 2-arylpropionic esters by palladium-catalyzed hydroesterification of styrene derivatives in molten salt media

D Zim, RF de Souza, J Dupont, AL Monteiro

文献索引：Zim, Danilo; De Souza, Roberto F.; Dupont, Jairton; Monteiro, Adriano L. Tetrahedron Letters, 1998 , vol. 39, # 39 p. 7071 - 7074

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被引用次数: 105

摘要

The palladium-catalyzed hydroesterification of styrene derivatives is performed in a two- phase system composed of 1-n-butyl-3-methylimidazoliumtetrafluoroborate salt (ionic phase) and isopropanol/cyclohexane (organic phase). Very high regioselectivities in 2- arylpropionic esters (≥ 99.5%) are obtained using a catalytic system composed of PdCl2 (PhCN) 2,(+)-neomenthyldiphenylphosphine (NMDPP) and p-toluenesulfonic acid under ...