Enzymatic resolution of 5??phenylselanyltetrahydro??2??furanone. enantioselective preparation of (r) and (s)?螃摸?valerolactone

GC Clososki, CE Costa, LJ Missio, QB Cass…

文献索引：Clososki, Giuliano C.; Costa, Carlos E.; Missio, Lauri J.; Cass, Quezia B.; Comasseto, Joao V. Synthetic Communications, 2004 , vol. 34, # 5 p. 817 - 828

全文：HTML全文

被引用次数: 16

摘要

Abstract Lipase??catalyzed lactonization of (2) provides both (R) and (S) enantiomers of 5?? phenylselenyltetrahydro??2??furanone (1) in good enantiomeric excess. The kinetic resolution was examined using PPL (Porcine pancreatic lipase), PSL (Amano PS, Pseudomonas sp. lipase), MML (Mucor miehei lipase), CRL (Candida rugosa lipase), CAL??B (Candida Antarctica lipase, type B) and Novozym 435 (immobilized C. antarctica lipase type B) in ...