Preparation of quarternary ammonium salt-tagged ferrocenylphosphine-imine ligands and their application to palladium-catalyzed asymmetric allylic substitution
A series of novel quarternary ammonium salt-modified chiral ferrocenylphosphine-imine ligands have been synthesized and the molecular structure of BIT5 has been determined by single-crystal X-ray diffraction. The applicability of these ligands in asymmetric C∗–C and C∗–N bond formation was demonstrated. High enantioselectivity was obtained in the Pd- catalyzed asymmetric substitution of 1, 3-diphenyl-2-propenyl acetate, with dimethyl ...
