New lead compounds for brassinosteroid biosynthesis inhibitors

…, T Asami, S Fujioka, N Murofushi, I Yamaguchi…

文献索引：Min, Yong Ki; Asami, Tadao; Fujioka, Shozo; Murofushi, Noboru; Yamaguchi, Isomaro; Yoshida, Shigeo Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 3 p. 425 - 430

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被引用次数: 74

摘要

The first brassinosteroid biosynthesis inhibitor is reported. Among newly synthesized triazole derivatives, 4-(4-chlorophenyl)-2-phenyl-3-(1, 2, 4-triazoyl) butan-2-ol (6) was found to inhibit the growth of cress seedlings, and this inhibition was recovered by the treatment of brassinolide, suggesting that compound 6 primarily inhibits brassinosteroid biosynthesis.