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The Journal of Organic Chemistry

Removal of N-arylsulfonyl groups from hydroxy. alpha.-amino acids

RC Roemmele, H Rapoport

文献索引:Roemmele, Renee C.; Rapoport, Henry Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2367 - 2371

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被引用次数: 130

摘要

OA quantitative yield can be obtained in 5 h at 50" C. bThese yields have not been optimized. boxyl group is destined to undergo reaction with an organometallic reagent.'Unfortunately, these protecting groups have frequently proved troublesome to remove. A variety of deprotection methods have been used, either hydrolytic2 or reductive, comprising dissolving metals or complex aluminum hydride^,^ electrochemical reduction: ...