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Behavioral approach to nondyskinetic dopamine antagonists: identification of seroquel

…, BM Migler, CJ Ohnmacht, AL Needles…

文献索引：Dostert; Langlois; Guerret; et al. European Journal of Medicinal Chemistry, 1980 , vol. 15, # 3 p. 199 - 205

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被引用次数: 40

摘要

... Journal of Medicinal Chemistry. ... Departments of Medicinal Chemistry, Pharmacology, and Drug Disposition and Metabolism, AstraZeneca Pharmaceuticals LP, PO Box 15437, Wilmington, Delaware 19850-5437. J. Med. Chem. ...

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1-Propanone,1-(1H-benzimidazol-2-yl)-2-methyl-(9CI)结构式

76098-79-8

1-Propanone,1-(...

~%

4,5-Dihydro-1-(1-methylethyl)-1,4-epoxy-1H,3H-(1,4)oxazepino(4,3-a)ben zimidazole结构式

76098-98-1

4,5-Dihydro-1-(...

Methanone,1H-benzimidazol-2-ylphenyl-结构式

955-41-9

Methanone,1H-be...

~%

1,4-Epithio-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-ph enyl-结构式

76099-31-5

1,4-Epithio-1H,...

2-(2-phenyl-1,3-dioxolan-2-yl)-1H-benzimidazole结构式

89521-84-6

2-(2-phenyl-1,3...

~%

1,4-Epithio-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-ph enyl-结构式

76099-31-5

1,4-Epithio-1H,...

1-(oxiran-2-ylmethyl)-2-(2-phenyl-1,3-dioxolan-2-yl)benzimidazole结构式

76099-45-1

1-(oxiran-2-ylm...

~%

1,4-Epithio-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-ph enyl-结构式

76099-31-5

1,4-Epithio-1H,...

2-(2-phenyl-1,3-dioxolan-2-yl)-1-(thiiran-2-ylmethyl)-1H-benzo[d]imidazole结构式

76099-46-2

2-(2-phenyl-1,3...

~22%

1,4-Epithio-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-ph enyl-结构式

76099-31-5

1,4-Epithio-1H,...

未登录结构式

89521-63-1

未登录

~%

brn 5651178结构式

76099-18-8

brn 5651178

未登录结构式

89521-62-0

未登录

~%

brn 5651178结构式

76099-18-8

brn 5651178

[1-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethyl)-5-nitro-1H-benzoimidazol-2-yl]-phenyl-methanol结构式

89521-64-2

[1-(2,2-Dimethy...

~%

brn 5651178结构式

76099-18-8

brn 5651178

1-氯-2,4-二硝基苯结构式

97-00-7

1-氯-2,4-二硝基苯

~%

brn 5651178结构式

76099-18-8

brn 5651178

(1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-5-nitro-1H-benzo[d]imidazol-2-yl)(phenyl)methanone结构式

89521-65-3

(1-((2,2-dimeth...

~%

brn 5651178结构式

76099-18-8

brn 5651178

1-(2-benzyloxyphenyl)-4,5-dihydro-1,4-epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole结构式

89521-71-1

1-(2-benzyloxyp...

~15%

brn 5608352结构式

76099-21-3

brn 5608352

1H-benzimidazol-2-yl-(2-methylphenyl)methanone结构式

76098-88-9

1H-benzimidazol...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-(2-m ethylphenyl)-结构式

76099-07-5

1,4-Epoxy-1H,3H...

Methanone,1H-benzimidazol-2-ylphenyl-结构式

955-41-9

Methanone,1H-be...

~%

1,4-Epoxy-1H-(1,4)oxazocino(4,3-a)benzimidazole, 3,4,5,6-tetrahydro-1- phenyl-结构式

76099-32-6

1,4-Epoxy-1H-(1...

(1H-benzo[d]imidazol-2-yl)(3-fluorophenyl)methanone结构式

76098-91-4

(1H-benzo[d]imi...

~%

4,5-Dihydro-1-(3-fluorophenyl)-1,4-epoxy-1H,3H-(1,4)oxazepino(4,3-a)be nzimidazole结构式

76099-10-0

4,5-Dihydro-1-(...

未登录结构式

76098-82-3

未登录

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-cycl ohexyl-结构式

76099-01-9

1,4-Epoxy-1H,3H...

Methanone,1H-benzimidazol-2-ylphenyl-结构式

955-41-9

Methanone,1H-be...

~%

1,4-Epoxy-1H,3H-(1,4)oxazonino(4,3-a)benzimidazole, 4,5,6,7-tetrahydro-1-phenyl-结构式

76099-33-7

1,4-Epoxy-1H,3H...

未登录结构式

76099-48-4

未登录

~%

1,4-Epoxy-1H,3H-(1,4)oxazonino(4,3-a)benzimidazole, 4,5,6,7-tetrahydro-1-phenyl-结构式

76099-33-7

1,4-Epoxy-1H,3H...

Methanone,1H-benzimidazol-2-ylphenyl-结构式

955-41-9

Methanone,1H-be...

~%

brn 5603142结构式

76099-34-8

brn 5603142

Methanone,1H-benzimidazol-2-ylphenyl-结构式

955-41-9

Methanone,1H-be...

~%

1,4-(Epoxymethanol)-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihy dro-1-phenyl-结构式

76099-35-9

1,4-(Epoxymetha...

Methanone,1H-benzimidazol-2-ylphenyl-结构式

955-41-9

Methanone,1H-be...

~%

1-(oxiran-2-ylmethyl)-2-(2-phenyl-1,3-dioxolan-2-yl)benzimidazole结构式

76099-45-1

1-(oxiran-2-ylm...

2-乙酰苯并咪唑结构式

939-70-8

2-乙酰苯并咪唑

~%

brn 1122749结构式

56969-23-4

brn 1122749

1-(1H-benzo[d]imidazol-2-yl)-2,2-dimethylpropan-1-one结构式

76098-80-1

1-(1H-benzo[d]i...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-(1,1-dimethylethyl)-结构式

76098-99-2

1,4-Epoxy-1H,3H...

(9ci)-alpha-乙基-1H-苯并咪唑-2-甲醇结构式

4857-00-5

(9ci)-alpha-乙基-...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-ethy l-结构式

76098-97-0

1,4-Epoxy-1H,3H...

1-Propanone,1-(1H-benzimidazol-2-yl)-(9CI)结构式

74126-96-8

1-Propanone,1-(...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-ethy l-结构式

76098-97-0

1,4-Epoxy-1H,3H...

1-Propanone,1-(1H-benzimidazol-2-yl)-(9CI)结构式

74126-96-8

1-Propanone,1-(...

2,2-二甲基-1,3-二氧环戊基-4-甲醇对甲基苯磺酸酯结构式

23737-51-1

2,2-二甲基-1,3-二氧环...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-ethy l-结构式

76098-97-0

1,4-Epoxy-1H,3H...

benzimidazol-2-yl 2-thienyl ketone结构式

76098-84-5

benzimidazol-2-...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-(2-t hienyl)-结构式

76099-03-1

1,4-Epoxy-1H,3H...

(1H-benzo[d]imidazol-2-yl)(2-methoxyphenyl)methanone结构式

76098-90-3

(1H-benzo[d]imi...

~%

brn 5620695结构式

76099-09-7

brn 5620695

(1H-benzo[d]imidazol-2-yl)(2-fluorophenyl)methanone结构式

76098-92-5

(1H-benzo[d]imi...

~%

brn 5608350结构式

76099-11-1

brn 5608350

2-benzoylimidazole结构式

38353-02-5

2-benzoylimidazole

~%

6,7-Dihydro-9-phenyl-6,9-epoxy-5H,9H-imidazo(2,1-c)(1,4)oxazepine结构式

76099-37-1

6,7-Dihydro-9-p...

甲醇结构式

67-56-1

甲醇

1-(2-hydroxyethyl)-2-benzoylbenzimidazole结构式

72562-62-0

1-(2-hydroxyeth...

~74%

1-methoxy-1-phenyl-3,4-dihydro-[1,4]oxazino[4,3-a]benzimidazole结构式

76099-39-3

1-methoxy-1-phe...

(1H-benzo[d]imidazol-2-yl)(3-chlorophenyl)methanone结构式

76098-85-6

(1H-benzo[d]imi...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-(3-c hlorophenyl)-结构式

76099-04-2

1,4-Epoxy-1H,3H...

未登录结构式

76098-89-0

未登录

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-(3-m ethoxyphenyl)-结构式

76099-08-6

1,4-Epoxy-1H,3H...

2,4-二氟硝基苯结构式

446-35-5

2,4-二氟硝基苯

~%

8-fluoro-4,5-dihydro-1-phenyl-1,4-epoxy-1H,3H-<1,4> oxazepino <4,3-a> benzimidazole结构式

76099-13-3

8-fluoro-4,5-di...

N-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-5-fluoro-2-nitroaniline结构式

76099-42-8

N-((2,2-dimethy...

~%

8-fluoro-4,5-dihydro-1-phenyl-1,4-epoxy-1H,3H-<1,4> oxazepino <4,3-a> benzimidazole结构式

76099-13-3

8-fluoro-4,5-di...

Methanone,1H-benzimidazol-2-ylphenyl-结构式

955-41-9

Methanone,1H-be...

~%

1-methoxy-1-phenyl-4,5-dihydro-3H-[1,4]oxazepino[4,3-a]benzimidazole结构式

76099-40-6

1-methoxy-1-phe...

phenyl(1-(3-((tetrahydro-2H-pyran-2-yl)oxy)propyl)-1H-benzo[d]imidazol-2-yl)methanone结构式

74549-20-5

phenyl(1-(3-((t...

~%

1-methoxy-1-phenyl-4,5-dihydro-3H-[1,4]oxazepino[4,3-a]benzimidazole结构式

76099-40-6

1-methoxy-1-phe...

甲醇结构式

67-56-1

甲醇

3-(2-benzoyl-benzimidazol-1-yl)-propanol结构式

74549-21-6

3-(2-benzoyl-be...

~19%

1-methoxy-1-phenyl-4,5-dihydro-3H-[1,4]oxazepino[4,3-a]benzimidazole结构式

76099-40-6

1-methoxy-1-phe...

Methanone,1H-benzimidazol-2-yl(4-chlorophenyl)-结构式

27099-25-8

Methanone,1H-be...

~%

brn 1154636结构式

56969-24-5

brn 1154636

1H-benzimidazol-2-yl-(4-fluorophenyl)methanone结构式

56969-31-4

1H-benzimidazol...

~47%

brn 1154635结构式

56969-25-6

brn 1154635

1H-benzimidazol-2-yl-(3-methylphenyl)methanone结构式

76098-87-8

1H-benzimidazol...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-(3-m ethylphenyl)-结构式

76099-06-4

1,4-Epoxy-1H,3H...

1-(1H-benzo[d]imidazol-2-yl)heptan-1-one结构式

76098-81-2

1-(1H-benzo[d]i...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-hexy l-结构式

76099-00-8

1,4-Epoxy-1H,3H...

1-phenyl-4,5-dihydro-1H,3H-1,4-epoxybenzo[4,5]imidazo[2,1-c][1,4]oxazepin-9-ol结构式

76099-24-6

1-phenyl-4,5-di...

硫酸二甲酯结构式

77-78-1

硫酸二甲酯

~%

4,5-dihydro-9-methoxy-1-phenyl-1,4-epoxy-1H,3H-<1,4> oxazepino <4,3-a> benzimidazole结构式

76099-15-5

4,5-dihydro-9-m...

(5-methoxy-1(3)H-benzoimidazol-2-yl)-phenyl-methanone结构式

15779-22-3

(5-methoxy-1(3)...

环氧溴丙烷结构式

3132-64-7

环氧溴丙烷

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-8-meth oxy-1-phenyl-结构式

76099-14-4

1,4-Epoxy-1H,3H...

4,5-dihydro-9-methoxy-1-phenyl-1,4-epoxy-1H,3H-<1,4> oxazepino <4,3-a> benzimidazole结构式

76099-15-5

4,5-dihydro-9-m...

phenyl-(5-trifluoromethyl-1(3)H-benzoimidazol-2-yl)-methanone结构式

76098-95-8

phenyl-(5-trifl...

环氧溴丙烷结构式

3132-64-7

环氧溴丙烷

~%

brn 5632391结构式

76099-16-6

brn 5632391

brn 5632392结构式

76099-17-7

brn 5632392

1H-benzimidazol-2-yl-(4-methylphenyl)methanone结构式

56969-32-5

1H-benzimidazol...

~%

brn 1150484结构式

56969-26-7

brn 1150484

Methanone, 1H-benzimidazol-2-yl(4-methoxyphenyl)-结构式

15449-89-5

Methanone, 1H-b...

~%

brn 1157965结构式

56969-27-8

brn 1157965

乙二醇结构式

107-21-1

乙二醇

(1-methyl-1H-benzoimidazol-2-yl)-phenyl-methanone结构式

13745-35-2

(1-methyl-1H-be...

~82%

1-methyl-2-(2-phenyl-1,3-dioxolan-2-yl)benzimidazole结构式

76099-38-2

1-methyl-2-(2-p...

(1H-benzo[d]imidazol-2-yl)(2-chlorophenyl)methanone结构式

76098-86-7

(1H-benzo[d]imi...

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-1-(2-c hlorophenyl)-结构式

76099-05-3

1,4-Epoxy-1H,3H...

(5-methoxy-1(3)H-benzoimidazol-2-yl)-phenyl-methanone结构式

15779-22-3

(5-methoxy-1(3)...

环氧溴丙烷结构式

3132-64-7

环氧溴丙烷

~%

1,4-Epoxy-1H,3H-(1,4)oxazepino(4,3-a)benzimidazole, 4,5-dihydro-8-meth oxy-1-phenyl-结构式

76099-14-4

1,4-Epoxy-1H,3H...

4,5-dihydro-9-methoxy-1-phenyl-1,4-epoxy-1H,3H-<1,4> oxazepino <4,3-a> benzimidazole结构式

76099-15-5

4,5-dihydro-9-m...

Methanone,1H-benzimidazol-2-ylphenyl-结构式

955-41-9

Methanone,1H-be...

~%

1,4-Epoxy-1H,3H-(1,4)thiazepino(4,3-a)benzimidazole, 4,5-dihydro-1-phe nyl-结构式

76099-30-4

1,4-Epoxy-1H,3H...

(1H-Benzoimidazol-2-yl)-m-tolyl-methanol结构式

88696-40-6

(1H-Benzoimidaz...

~%

1H-benzimidazol-2-yl-(3-methylphenyl)methanone结构式

76098-87-8

1H-benzimidazol...

邻苯二胺(OPD)结构式

95-54-5

邻苯二胺(OPD)

~%

1H-benzimidazol-2-yl-(3-methylphenyl)methanone结构式

76098-87-8

1H-benzimidazol...

4-氯-3-硝基三氟甲苯结构式

121-17-5

4-氯-3-硝基三氟甲苯

~%

brn 5632392结构式

76099-17-7

brn 5632392

phenyl-(5-trifluoromethyl-1(3)H-benzoimidazol-2-yl)-methanone结构式

76098-95-8

phenyl-(5-trifl...

环氧溴丙烷结构式

3132-64-7

环氧溴丙烷

~%

brn 5632391结构式

76099-16-6

brn 5632391

brn 5632392结构式

76099-17-7

brn 5632392

2-(4-fluoro-α-hydroxybenzyl)benzimidazole结构式

35538-21-7

2-(4-fluoro-α-h...

~%

1H-benzimidazol-2-yl-(4-fluorophenyl)methanone结构式

56969-31-4

1H-benzimidazol...

邻苯二胺(OPD)结构式

95-54-5

邻苯二胺(OPD)

~%

1H-benzimidazol-2-yl-(4-fluorophenyl)methanone结构式

56969-31-4

1H-benzimidazol...


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