Radiolabeled melanin-binding peptides are safe and effective in treatment of human pigmented melanoma in a mouse model of disease

E Dadachova, T Moadel…

文献索引：El Aissi, Radhia; Liu, Jianrong; Besse, Sophie; Canitrot, Damien; Chavignon, Olivier; Chezal, Jean-Michel; Miot-Noirault, Elisabeth; Moreau, Emmanuel ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 468 - 473

全文：HTML全文

被引用次数: 28

摘要

... States, and there are an estimated 100,000 cases worldwide.2,3 Metastatic melanoma is al- ... feasibility of targeting melanin, an intracellular melanocyte pigment, to deliver cytotoxic radia- tion to ... on an automatic peptide synthesizer, using stan- dard Fmoc/HBTU chemistry on ring ...