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Synthesis and analgesic activity of some triazoles and triazolothiadiazines

G Turan-Zitouni, ZA Kaplancikli, K Erol, FS Kilic

文献索引:Turan-Zitouni; Kaplancikli; Erol; Kilic Farmaco, 1999 , vol. 54, # 4 p. 218 - 223

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被引用次数: 195

摘要

The synthesis of some triazoles and triazolothiadiazines starting from (5, 6, 7, 8- tetrahydronaphthalen-2-yl) oxyacetic acid is described. The chemical structure of the compounds were elucidated by analytical, IR, 1H NMR and mass spectral studies. Some of the newly synthesized compounds were tested for analgesic activity and compounds 5b, 5c, and 5d exhibited promising analgesic activity.