Tetrahedron Letters

Copper-mediated oxidative tandem reactions with molecular oxygen: synthesis of 2-arylbenzoxazinone derivatives from indoles

M Yamashita, A Iida

文献索引：Yamashita, Mitsuaki; Iida, Akira Tetrahedron Letters, 2014 , vol. 55, # 18 p. 2991 - 2993

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被引用次数: 6

摘要

Abstract We developed an efficient method for the transformation of indoles by utilizing a copper catalyst and molecular oxygen as the oxidant. The transformation involves a tandem oxidative process of 2-arylindoles. Our reaction afforded a variety of N-benzoyl anthranilic acids and benzoxazinones. Our investigation revealed that the choice of solvent and additives is critical in these reactions.