Thioamide derivatives of cannabinoids. A study of the influence of the thioamide function on regiochemistry in the synthesis of thioamide cannabinoids from 2, 4?? …

…, T Jagodziński, M Krolikowska

文献索引：Sosnicki, Jacek; Jagodzinski, Tadeusz; Krolikowska, Miroslawa Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 4 p. 1033 - 1041

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被引用次数: 5

摘要

Abstract Several thiocarbamoyl derivatives of cannabinoids were obtained in the collidine- catalysed condensation of 2, 4-dihydroxybenzothioamides with citral and citronellal. The thioamide function was found to change the regioselective preferences of the reaction as compared with the known cannabinoid syntheses from hydroxyacetophenones. The experimental results and theoretical (FMO theory) considerations made it possible to ...