Canadian journal of chemistry

Thiol functionalization of surfaces for biosensor development

ME McGovern, M Thompson

文献索引：McGovern, Mark E.; Thompson, Michael Canadian Journal of Chemistry, 1999 , vol. 77, # 10 p. 1678 - 1689

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被引用次数: 35

摘要

The immobilization of biomolecules on substrate surfaces for biosensor development requires linking molecules that must meet a specific set of criteria. Two such agents based on bifunctional alkyltrichlorosilane structures, 1-bromo-11-(trichlorosilyl)-undecane and 1- (thiotrifluoroacetato)-11-(trichlorosilyl)-undecane, are employed to generate thiol- functionalized surfaces either by nucleophilic substitution followed by reduction (bromine- ...