Palladium-Catalyzed cross-Benzannulation of Aminoenynes with Diynes. Highly Regioselective Synthesis of Polysubstituted Anilines

S Saito, N Uchiyama, V Gevorgyan…

文献索引：Saito, Shinichi; Uchiyama, Naoyuki; Gevorgyan, Vladimir; Yamamoto, Yoshinori Journal of Organic Chemistry, 2000 , vol. 65, # 14 p. 4338 - 4341

全文：HTML全文

被引用次数: 28

摘要

Polysubstituted anilines were prepared by the palladium-catalyzed cross-benzannulation of conjugated aminoenynes 1-4 with diynes 8. The reaction proceeded in a highly regioselective manner under mild conditions, and the anilines were obtained as single regioisomers. Our method complements the well-known precedures for the preparation of polysubstituted anilines which are widely used in organic synthesis.