Tetrahedron

Regiospecific substitution of the carbon–boron bond of tris (4-methylfuran-3-yl) boroxine: a model ring C→ BC→ ABC approach towards eudesmanolides

CY Yick, HNC Wong

文献索引：Yick, Chung-Yan; Wong, Henry N.C Tetrahedron, 2001 , vol. 57, # 32 p. 6935 - 6940

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被引用次数: 13

摘要

A synthetic study of eudesmanolides was performed utilizing a Suzuki coupling reaction of tris (4-methylfuran-3-yl) boroxine (6) as the pivotal step. The other key reactions involved Friedel–Crafts acylation, Wacker–Tsuji reaction and aldol condensation. In this Ring C→ BC→ ABC approach, a model compound 3 towards the synthesis of eudesmanolides 11, 13- dihydrotubiferin (1) and artogallin (2) was realized. In another model study, the five- ...