4-Acetylamino-3-(imidazol-1-yl)-benzoic acids as novel inhibitors of influenza sialidase
…, PW Smith, SL Sollis, N Taylor, AJ Wonacott
文献索引：Howes, Peter D.; Cleasby, Anne; Evans, Derek N.; Feilden, Helen; Smith, Paul W.; Sollis, Steven L.; Taylor, Neil; Wonacott, Alan J. European Journal of Medicinal Chemistry, 1999 , vol. 34, # 3 p. 225 - 234
Two methods for the synthesis of 4-acetylamino benzoic acids substituted at the 3-position with imidazoles are described. Many of the compounds are inhibitors of influenza virus sialidases with levels of activity similar to the recently described 4-acetylamino-3-guanidino- benzoic acid (BANA 113).
