Tetrahedron Letters

Highly selective synthesis of libraries of 1, 2-disubstituted benzimidazoles using silica gel soaked with ferric sulfate

S Paul, B Basu

文献索引：Paul, Susmita; Basu, Basudeb Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4130 - 4133

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被引用次数: 27

摘要

An efficient and highly selective synthesis of functionalized 1, 2-benzimidazoles has been developed under solvent-free conditions at ambient temperature using eco-friendly ferric sulfate soaked with silica [iron (III) sulfate–silica]. Recycling of the solid support up to six runs was investigated with appreciable yield and selectivity of the product.