The Journal of organic chemistry

Aerobic oxidative amidation of aromatic and cinnamic aldehydes with secondary amines by CuI/2-pyridonate catalytic system

M Zhu, K Fujita, R Yamaguchi

文献索引：Zhu, Mingwen; Fujita, Ken-Ichi; Yamaguchi, Ryohei Journal of Organic Chemistry, 2012 , vol. 77, # 20 p. 9102 - 9109,8

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被引用次数: 38

摘要

A simple and convenient CuI/2-pyridonate catalytic system for the oxidative amidation of aldehydes with secondary amines has been developed. With this system, a variety of useful arylamides have been synthesized in moderate to good yields in the presence of small amount of copper catalyst and the pyridonate ligand, generating only water as a coproduct. Synthesis of cinnamamides was also achieved by the reactions of cinnamaldehydes with ...