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Microwave-assisted one-pot synthesis of benzothiazole and benzoxazole libraries as analgesic agents

C Praveen, A Nandakumar, P Dheenkumar…

文献索引:Praveen; Nandakumar; Dheenkumar; Muralidharan; Perumal Journal of Chemical Sciences, 2012 , vol. 124, # 3 p. 609 - 624

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被引用次数: 40

摘要

Abstract Microwave-assisted synthesis of benzothiazole and benzoxazole libraries via PIFA promoted cyclocondensation of 2-aminothiophenols/2-aminophenols with aldehydes under one-pot condition in good to excellent yields was achieved. Twenty compounds have been investigated for their analgesic activity and showed moderate to good activity. Graphical Abstract Microwave-assisted synthesis of benzothiazole and benzoxazole libraries via ...