Heteroatom Chemistry

Synthesis and characterization of chroman??containing compounds and their preliminary assessment of cytotoxicity toward two human cancer cell lines

Y Tang, J Wei, W Zhong, X Liu

文献索引：Tang, Ying; Wei, Jie; Zhong, Wei; Liu, Xiaoming Heteroatom Chemistry, 2010 , vol. 21, # 6 p. 423 - 429

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被引用次数: 3

摘要

Abstract A series of chroman derivatives were synthesized by employing o-methyl phenol as a precursor. These compounds were fully characterized using IR, NMR spectroscopic techniques, and elemental analysis. Mechanisms for the formation of the chroman moiety of these compounds were also proposed. MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5- diphenyltetrazolium bromide) assay was used to estimate their cytotoxicity toward two ...