Tetrahedron letters

Solid phase synthesis of aryl amines

CA Willoughby, KT Chapman

文献索引：Willoughby, Christopher A.; Chapman, Kevin T. Tetrahedron Letters, 1996 , vol. 37, # 40 p. 7181 - 7184

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被引用次数: 86

摘要

A method for the solid phase synthesis of aryl amines is reported. The method involves a palladium mediated coupling reaction between aryl bromides and amines. The products are isolated in high purity and good yields. This method should prove to be a useful tool for constructing combinatorial libraries containing the aryl amine moiety.