Tetrahedron

Highly diastereoselective synthesis of tetrahydrobenzofuran derivatives by palladium-catalyzed reaction of propargylic esters with substituted β-dicarbonyl compounds

M Yoshida, M Higuchi, K Shishido

文献索引：Yoshida, Masahiro; Higuchi, Mariko; Shishido, Kozo Tetrahedron, 2010 , vol. 66, # 14 p. 2675 - 2682

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被引用次数: 33

摘要

Reactions of propargylic esters with 2-substituted cyclohexane-1, 3-diones and 2- oxocyclohexanecarboxylic esters in the presence of palladium catalyst are described. Substituted tetrahydrobenzofuran derivatives having a quaternary carbon stereocenter were synthesized in a highly diastereoselective manner.