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Synthesis and biological activity of carboxylic acid derivatives carrying sulfur-containing groups in the β-position

…, VM Bystrova, TP Vasil'eva, OV Kil'disheva

文献索引:Znamenskii, V. V.; Efremov, A. D.; Bystrova, V. M.; Vasil'eva, T. P.; Kil'disheva, O. V. Pharmaceutical Chemistry Journal, 1986 , vol. 20, # 7 p. 496 - 500 Khimiko-Farmatsevticheskii Zhurnal, 1986 , vol. 20, # 7 p. 843 - 847

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摘要

We have previously reported [3] the synthesis of new heterocyclic compounds: 1, 2-oxathio! an-5-one 2-oxides and 2, 1-benzoxathiol-3-one 1-oxide. In the present work, we have studied reactions involving splitting of these compounds by certain nucleophilic reagents. As in the case of cyclic anhydrides of 8-sulfocarboxylic acids [9], their splitting by nucleophiles does not occur at the O-SO bond, but at the O-CO bond with the formation of the ...