Discovery and preliminary SAR studies of a novel, nonsteroidal progesterone receptor antagonist pharmacophore

CLF Pooley, JP Edwards, ME Goldman…

文献索引：Journal of Medicinal Chemistry, , vol. 41, # 18 p. 3461 - 3466

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被引用次数: 57

摘要

... Journal of Medicinal ... Departments of Medicinal Chemistry, New Leads Discovery, and Endocrine Research, Ligand Pharmaceuticals Inc., San Diego, California. J. Med. Chem. ... Chemistry. The initial lead, LG001447 (3), was screened for activity on various intracellular receptors. ...