An Efficient Large-Scale Process for the Human Leukocyte Elastase Inhibitor, DMP 7771

L Storace, L Anzalone, PN Confalone…

文献索引：Organic Process Research and Development, , vol. 6, # 1 p. 54 - 63

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被引用次数: 30

摘要

... will discuss in turn the synthesis of fragments 1 and 2 and conclude by describing a procedure for their ... A total of 190 kg of DMP 777 were prepared by this process. ... completion criterion of less than 5% of 6). The lower (aqueous) layer was separated, and the organic phase was ...