Tetrahedron

Synthesis and insect antifeedant activity of 2-substituted 2, 3-dihydrofuran-3-ols and butenolides (Part II)

EA klein Gebbinck, GA Stork, BJM Jansen, A de Groot

文献索引：Klein Gebbinck, Edwin A.; Stork, Gerrit A.; Jansen, Ben J. M.; De Groot, Aede Tetrahedron, 1999 , vol. 55, # 36 p. 11077 - 11094

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被引用次数: 12

摘要

The introduction of a hydroxy group at C-13 of the clerodane skeleton is proposed as a strategy to potentially increase the antifeedant activity of simple analogs. This idea is applied to clerodane analogs with furan or butenolide type sidechains and therefore syntheses were developed for several types of 3-alkyl-substituted butenolides, 3-alkyl-substituted-3- hydroxybutenolides and 3-hydroxytetrahydrofuran derivatives. The antifeedant activity ...