As a privileged fragment, quinoline is a ubiquitous subunit in many quinoline-containing natural products with remark- able biological activities.1—6) Members of this family have wide applications in medicinal chemistry, being used as antimalarial, antiinflammatory agents, antiasthamatic, anti- bacterial, antihypertensive, and tyrosine kinase inhibiting agents.1—6) In addition, quinolines are valuable synthons used for the preparation of nano- and meso-structures with en- ...