Tetrahedron letters

The first separation and stereochemical determination of bis (α-hydroxyalkyl) phosphinic acids diastereoisomers

B Kaboudin, H Haghighat

文献索引：Kaboudin, Babak; Haghighat, Hamideh Tetrahedron Letters, 2005 , vol. 46, # 46 p. 7955 - 7957

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被引用次数: 24

摘要

A separation of bis (α-hydroxyalkyl) phosphinic acid diastereoisomers is described. A novel method for the determination stereochemistry of bis (α-hydroxyalkyl) phosphinic acid diastereoisomers has been developed. The stereochemistry of one diastereoisomer was confirmed after converting to the corresponding methyl ester using trimethyl orthoformate.