A variety of (Z)-[(2H-chromen-3-yl) methylene] azolidinones 6a–t bearing thiazolidine-2, 4- dione, rhodanine or hydantoin scaffolds were designed and synthesized as potential anticancer agents. Inhibitory effect of synthesized compounds 6a–t on the viability of cancer and non-cancer cells was assessed using MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5- diphenyltetrazolium bromide) reduction assay. The SAR study revealed that the N- ...
