Tetrahedron

Ni (0)/NHC-catalyzed amination of N-heteroaryl methyl ethers through the cleavage of carbon‒oxygen bonds

…, A Yasutome, K Yamakawa, T Shimasaki, N Chatani

文献索引：Tobisu, Mamoru; Yasutome, Ayaka; Yamakawa, Ken; Shimasaki, Toshiaki; Chatani, Naoto Tetrahedron, 2012 , vol. 68, # 26 p. 5157 - 5161

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被引用次数: 34

摘要

Ni (0)/NHC-based catalyst system can promote the amination of N-heteroaryl methyl ethers via the cleavage of normally unreactive carbon–oxygen bonds. Electron-deficient N- heteroarenes including pyridine, quinoline, isoquinoline, and quinoxaline undergo amination to afford aminopyridine and related heteroarenes, which constitute an important class of compounds.