Unexpected result in the reaction of 3-amino-3-thioxopropanamides with 2-anilinomethylene derivatives of 1, 3-dicarbonyl compounds. synthesis of pyrimidine- …
VV Dotsenko, KA Frolov, SG Krivokolysko…
文献索引：Dotsenko; Frolov; Krivokolysko; Polovinko Chemistry of Heterocyclic Compounds, 2013 , vol. 49, # 3 p. 440 - 451
The interaction of 3-amino-3-thioxopropanamides with 2-anilinomethylene derivatives of dimedone, 1, 3-cyclohexanedione and Meldrum's acid led to the formation of 2-(2-amino-2- oxoethyl)-6-thioxo-1, 6-dihydropyrimidine-5-carboxamides. The latter were alkylated in alkaline medium with the formation of 4-(alkylthio) pyrimidine-5-carboxamide derivatives. Keywords: 3-amino-3-thioxopropanamides, pyrimidine-5-carboxamides, thiomalonamides ...
