Tetrahedron Letters

Synthesis of symmetrical triarylphosphines from aryl fluorides and red phosphorus: scope and limitations

TL Schull, SL Brandow, WJ Dressick

文献索引：Schull, Terence L.; Brandow, Susan L.; Dressick, Walter J. Tetrahedron Letters, 2001 , vol. 42, # 32 p. 5373 - 5376

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被引用次数: 14

摘要

The reaction of aryl fluorides with phosphide anion, generated in situ from the reduction of red phosphorus by lithium metal in liquid ammonia, gave symmetrical triarylphosphines in fair to good yields. Phosphonodiamide, sulfonamide, 2-oxazolyl, and nitrile groups were stable to the reaction conditions, while nitro and bromo substituents were not. para- Substituted aryl fluorides gave higher yields than meta-substituted aryl fluorides, and ortho ...