Liebigs Annalen der Chemie

Synthesis and stereochemistry of some new diazatricyclic compounds

P Scheiber, P Nemes

文献索引：Scheiber, Pal; Nemes, Peter Liebigs Annalen der Chemie, 1994 , # 10 p. 1033 - 1036

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被引用次数: 17

摘要

Abstract The diazatricyclic ketone 3 was synthesized by a double Mannich condensation starting from 2-quinolizidone (2). Reductions of 3 by complex hydrides and hydrazine gave a mixture of isomeric amino alcohols rac-4/5 and the diamine 6, respectively. Compounds rac- 4 and rac-5 could be separated by selective acylation with 4-chlorobenzoyl chloride due to the fundamental steric differences in the N [RIGHTWARDS ARROW] O acyl transfer ...