Alternate synthesis of a β-3 adrenergic receptor agonist

RW Scott, DE Fox, JW Wong…

文献索引：Organic Process Research and Development, , vol. 8, # 4 p. 587 - 592

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被引用次数: 7

摘要

... The final two-step procedure started with amide hydrolysis by NaOH in aqueous ethanol. ... In addition, the dimethylpyrrole added significant organic solubility to the compounds in this notoriously ... From a process standpoint, the synthesis is a promising and viable alternative to the ...