Bakers' yeast-catalyzed reductive cleavage of 3-aryl-2, 1-benzisoxazoles and its quaternary salts: an efficient green synthesis of 2-aminobenzophenones
Abstract 3-Aryl-2, 1-benzisoxazoles and its salts underwent reductive cleavage of the N–O bond leading to 2-aminobenzophenones with bakers' yeast under non-fermenting conditions in aqueous media. The procedure gives excellent yields of 2-alkylamino-and 2- aminobenzophenones. Graphical Abstract