Chemical Communications

Practical divergent synthesis of all possible regioisomers of myo-inositol trisphosphates

SK Chung, YT Chang, KH Sohn

文献索引：Chung, Sung-Kee; Chang, Young-Tae; Sohn, Kwang-Hoon Chemical Communications, 1996 , # 2 p. 163 - 164

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被引用次数: 10

摘要

D-myo-Inositol- 1,4,5-trisphosphate [I( 1,4,5)P3] receptors are a homologous family of tetrameric ligand-gated Ca2+ channels which allow mobilization of intracellular Ca2+ stores in response to activation of cell-surface receptors linked to I( 1,4,5)P3 generation. Although the ligand recognition site of the IP3 receptors appears to be in the N-terminal region, the exact nature of the molecular interactions is not understood. Several other IP3s are also found in living systems, and ...