Abstract A number of biologically relevant O 4-phospho-L-tyrosine-containing peptides have been synthesized by either the global phosphorylation of the side-chain-unprotected L- tyrosine moiety in presynthesized resin-bound peptides or alternatively by the incorporation of suitably protected O 4-phospho-L-tyrosine building blocks in the continuous-flow method of Fmoc solid-phase peptide synthesis. Different phosphate-protecting groups have been ...
