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Quinazolinone fungal efflux pump inhibitors. Part 2: In vitro structure–activity relationships of (N-methyl-piperazinyl)-containing derivatives

…, J Barnard, R Jankowska, R Singh, D Madsen…

文献索引:Watkins, William J.; Lemoine, Remy C.; Chong, Lee; Cho, Aesop; Renau, Thomas E.; Kuo, Bonnie; Wong, Vickie; Ludwikow, Maria; Garizi, Negar; Iqbal, Nadeem; Barnard, John; Jankowska, Renata; Singh, Rajeshwar; Madsen, Deidre; Lolans, Karen; Lomovskaya, Olga; Oza, Uma; Dudley, Michael N. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 20 p. 5133 - 5137

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被引用次数: 22

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Structure–activity relationships of a novel series of fungal efflux pump inhibitors with respect to potentiation of the activity of fluconazole against strains of Candida albicans and Candida glabrata over-expressing ABC-type efflux pumps are systematically explored.