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A diene-transmissive approach to the quassinoid skeleton

…, B Hill, P Dubé, S Gingras

文献索引:Spino, Claude; Hill, Bryan; Dube, Pascal; Gingras, Stephane Canadian Journal of Chemistry, 2003 , vol. 81, # 1 p. 81 - 108

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被引用次数: 25

摘要

Several tetracyclic molecules were prepared by diene-transmissive Diels Alder cycloadditions. Control over the stereochemical outcome of the cycloaddition was achieved and the structural features of the precursors affecting the stereochemistry is discussed. Useful information was gathered concerning the factors governing this stereocontrol, which will be indispensable for the future of this strategy. Key words: quassinoid, anticancer ...