N-Methoxy-N-methyl amides, or Weinreb amides, 1 have been widely used as versatile synthetic intermediates in organic syntheses. 2 These amides serve as excellent acylating agents for organolithium or organomagnesium reagents and as robust aldehyde group equivalents. 3 The utility of Weinreb amides has been extended to the preparation of N- protected amino aldehydes, useful intermediates for many chemoselective ...
