An expedient synthesis of novel 2-substituted thiazolo [4, 5-f] isoquinolines/quinolines and benzo [1, 2-d: 4, 3-d′] bisthiazoles and their potential as inhibitors of …
M Chakrabarty, A Mukherji, S Karmakar, R Mukherjee…
Abstract An efficient, general synthesis of 2-substituted thiazolo [4, 5-f] isoquinolines, thiazolo [4, 5-f]-quinolines and benzo [1, 2-d: 4, 3-d'] bisthiazoles has been accomplished from 5-nitroisoquinoline/quinoline and 6-nitrobenzothiazole, respectively, and all the products have been thoroughly identified spectroscopically (IR, 1H and 13C NMR, LR/HR EI/FAB/ESI-MS). The synthesis of thiazolo [4, 5-f] isoquinolines constitutes the first ...