Stereoselective synthesis of sarmentine

…, AU Ishbaeva, AS Sunagatullina, VV Zorin

文献索引：Shakhmaev; Ishbaeva; Sunagatullina; Zorin Russian Journal of General Chemistry, 2011 , vol. 81, # 9 p. 1915 - 1917

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被引用次数: 5

摘要

Natural (2E, 4E)-dienamides of Piperaceae and Echinacea species have a broad spectrum of therapeutic action, and in the past decade they attracted a wide attention [1–7]. Sarmentine, the 1-[(2E, 4E)-deca-2, 4-dienoyl] pyrrolidine, was first isolated from the Piper sarmentosum fruits [8]. It possesses sedative, analgesic, and antibacterial activities [9]. Recently it was found to manifest antitubercular and antiplazmodial activities [10].