Synlett

Transition metals in organic synthesis, part 96. First total synthesis of streptoverticillin: unambiguous confirmation of the absolute configuration

C Thomas, O Kataeva, HJ Knölker

文献索引：Thomas, Claudia; Kataeva, Olga; Knoelker, Hans-Joachim Synlett, 2011 , # 18 p. 2663 - 2666

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被引用次数: 12

摘要

Abstract Using an iron-mediated construction of the carbazole framework, the first synthesis of streptoverticillin is described and the absolute configuration of the natural product is confirmed. The synthesis exploits a novel oxygen-mediated aromatization of tricarbonyliron- coordinated dihydrocarbazoles. Moreover, non-natural (R)-streptoverticillin is prepared for comparison.