Ruthenium-Catalyzed Selective α, β-Deuteration of Bioactive Amines

…, S Imm, H Neumann, J Atzrodt, V Derdau…

文献索引：Derdau, Volker; Atzrodt, Jens; Zimmermann, Jochen; Kroll, Carsten; Brueckner, Francois Chemistry - A European Journal, 2009 , vol. 15, # 40 p. 10397 - 10404

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被引用次数: 31

摘要

A novel and convenient protocol for the catalytic hydrogen–deuterium exchange of biologically active tertiary amines utilizing the borrowing hydrogen methodology has been developed. In the presence of the readily available Shvo catalyst, excellent ...