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Tetrahedron

Synthesis of ω-aminooxy acids by oxygen-alkyl fission of lactones: An improved synthesis of dl-canaline

C Gilon, Y Knobler, T Sheradsky

文献索引:Gilon,C. et al. Tetrahedron, 1967 , vol. 23, p. 4441 - 4447

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被引用次数: 5

摘要

(Received 20 February I967 : accepted for publication 14 March 1967) ... Abstract-Lactones were found to react with benzophenone oxime salt to give odiphenylmethylidene- aminooxy acids which were hydrolyzed to the corresponding r+aminooxy acids. The reaction was applied to an tfftcient syntheses of or-canaime. ... ~-AMIN~~XY acids are of interest, ie owing to their structural relationship to canaline and cycloserine. We wish to report a method for ...