Preparation of Phosphonomethyl Ethers Derived from 2-Phenylethanol and Its Amino Derivatives

M Krečmerová, A Holý

文献索引：Krecmerova, Marcela; Holy, Antonin Collection of Czechoslovak Chemical Communications, 1995 , vol. 60, # 4 p. 659 - 669

全文：HTML全文

被引用次数: 3

摘要

Abstract A series of compounds derived from the acyclic nucleoside antiviral 9-(2- phosphonomethoxyethyl) adenine (PMEA), in which the adenine ring is replaced by phenyl, 4-aminophenyl, 3-aminophenyl or 3, 5-diaminophenyl group, has been prepared starting from the corresponding phenethyl alcohols. 2-(3-Aminophenyl) ethanol was prepared from 3- nitrobenzoyl chloride using the Arndt-Eistert reaction. The primarily formed diazoketone Ia ...