Tetrahedron letters

Cupric sulfate pentahydrate (CuSO 4· 5H 2 O): a mild and efficient catalyst for tetrahydropyranylation/depyranylation of alcohols and phenols

AT Khan, LH Choudhury, S Ghosh

文献索引：Khan, Abu T.; Choudhury, Lokman H.; Ghosh, Subrata Tetrahedron Letters, 2004 , vol. 45, # 42 p. 7891 - 7894

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被引用次数: 54

摘要

Various alcohols and phenols can be smoothly converted to the corresponding THP ethers using 20mol% CuSO4· 5H2O under mild reaction conditions at room temperature. Some of the major advantages of this procedure are nonaqueous work-up, very good yields, less expensive catalyst and compatibility with other protecting groups.