With the advantage of the method using two immiscrible solvents and half-equivalent amount of the resolving agent, higher optical purity can be obtained than in cases of any other resolution via diastereoisomeric salt formation, besides it is a faster procedure for resolution of a new racemate as well.
![(R)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole monohydrochloride结构式](https://image.chemsrc.com/caspic/460/16595-76-9.png)