Ib, n= 3 mouse by the procedure of Rane, et aZ. 13 Deaths occurring on days 2-5 after infection were attributed to drug action; infected control animals did not die before day 6. These compounds were highly toxic at 160-640 mg/kg. They exhibited negligible antimalarial action at lower doses, were not curative at 40-640 mg/kg, and increased survival time from 0.3-2.9 days only. Substitution by phenyl or trifluoromethyl at position 2 ...
