Antibacterial activity of and resistance to small molecule inhibitors of the ClpP peptidase

CL Compton, KR Schmitz, RT Sauer…

文献索引：Zeiler, Evelyn; Korotkov, Vadim S.; Lorenz-Baath, Katrin; Boettcher, Thomas; Sieber, Stephan A. Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 2 p. 583 - 591

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被引用次数: 18

摘要

... Given the potent antibacterial activity of these compounds and their medicinal potential, we sought to identify innate mechanisms of ... Sieber and co-workers reported similar observations wherein β-lactones that suppress virulence factor production in S. aureus in the ...