Synthesis of Metabolites of the Ah Receptor Ligand 6??Formylindolo [3, 2??b] carbazole

N Wahlström, I Romero…

文献索引：Wahlstroem, Niklas; Romero, Ivan; Bergman, Jan European Journal of Organic Chemistry, 2004 , # 12 p. 2593 - 2602

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被引用次数: 17

摘要

Abstract Synthesis of the five mono-and di-hydroxylated metabolites of the aryl hydrocarbon receptor high affinity ligand 6-formylindolo [3, 2-b] carbazole is described. The structures of the metabolites were unequivocally established as 2-hydroxy-, 8-hydroxy-, 2, 10-dihydroxy-, 4, 8-dihydroxy-and 2, 8-dihydroxyindolo [3, 2-b] carbazole-6-carboxaldehyde.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)