Total synthesis of milbemycin. beta. 3

…, SR Schow, JD Bloom, AS Thompson…

文献索引：Smith, Amos B.; Schow, Steven R.; Bloom, Jonathan D.; Thompson, Andrew S.; Winzenberg, Kevin N. Journal of the American Chemical Society, 1982 , vol. 104, # 14 p. 4015 - 4018

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被引用次数: 77

摘要

Milbemycin p3 (la), the simplest member of a family of some 13 architecturally novel macrolide antibiotics structurally related to the avermectins? was first isolated in 1975 by Mishima et from Streptomyces B-41-146. Subsequent screening demonstrated that this antibiotic complex possessed remarkably potent pesticidal activitf against a host of agricultural pests, including aphids, lava1 forms of insects of the order Lepidopera, mites, ...